Pacific Pharmaceuticals Limited

Introductin First Time in PAKSITAN
Apridin® 10% Gel(Idoxuridine + Dimelhyl Sulfoxide)
Penetrates Deeper - Treats Herpes Faster
When viral infection is limited to the skin
Topical therapy should be preferred ¹
Because of
Convenience Reduced systemic side effects Higher concentration of anti-viral agent at the site of infection Greater efficacy

Apridin fulfills this criteria exclusively

Apridin contains Idoxuridine, a topical virustatic agent, worldwide approved and clinically used for the treatment of Herpes Simplex Labialis & Herpes Zoster infections.1 Mode of action : Idoxuridine (Apridin) is incorporated into viral DNa instead of thymidine, so inhibiting replication of the virus. 2 Dimethyl Sulfoxide, the most appropriate & safe lipophilic drug vehicle that strongly enhances the drug penetration through the skin to manage Herpes Simplex virus infections and Herpes Zoster infections effectively with good tolerability. ¹ Apridin significantly reduces the severity of viral infections.¹ Apridin is more adherent to the skin, thus allowing a higher local bioavailability of drug,¹

Idoxuridine (Apridin) demonstrates remarkably shorter healing time than topical acyclovir & placebo.


The study results showed a faster and more marked regression of symtomatology with idoxuridine (Apridin) than with placebo.3	There was no statistically significan diference in the modification of clinical critaria of efficacy between topical acyclovir and placebo treated patients.4

In HSV-1 infection, topical idoxuridine (Apridin) is as effective as, but more tolerated, than oral acyclovir.


The two treatments appeared almost equally effective, although a statistically significant lower time to loss of hard crust was observed in idoxuridine (Apridin) treared patients.5	When the treatment was started "early" in the prodrome or erythema stage, idoxurine (Apridin) reduced the duration of pain & lesions significantly greater than an oral acyclovir treatment. 6

Apridin does not cause renal failure & neurotoxicity as reported with oral acyclovir.
Oral Acyclovir shows acute renal failure and neurotoxicity.7, 8

Apridin effectively treats Herpes Zoster
Idoxuridine ( Apridin ) had a considerable effect on zoster, both in shortening the healing time and in reducing
the duration of zoster neuralgia.9

Apridin 10% Gel

Quick Relief in Patients Suffering From


Offers better local bioavailability Greater efficacy Cosmetically ideal Easy to apply, just with a help of finger and doesn't require a brush		Download