| Napreben® HARD ON THE PAIN |
SOFT ON THE GUT |
| Provides quick pain relief through rapid absorption. |
Betaine & Sodium Partially neutralize the gastric acidity
thus reducing
harmful effects of anti-inflammatory |
| Napreben® HARD ON THE PAIN |
Napreben® SOFT ON THE GUT |
| (Naproxen Betaine Sodium) Betaine makes naproxen to be rapidly absorbed thus achieves quick serum concentration & better bioavailability4 so onset of pain relief occurs just in 15 minutes |
Carboxylic acid of Naproxen is in
the undissociated
form in Napreben hence,direct gastrolesive effect is reduced |
| |
owest
incidence of side effects makes Napreben® well tolerated. |
| PEAK
SERUM TIME |
NSAID'S |
SIDE
EFFECTS 1,2,3 |
| 2-3 HRS. |
Diclofenac |
 |
Napreben |
3.67% |
| 2-4 HRS. |
Naproxen |
Diclofenac |
21-31.2% |
| 1-2 HRS. |
Naproxen Na+ |
Naproxen |
25% |
| 1 HRS. |
Napreben® |
Naproxen
Na+ |
20% |
| 3-5 HRS. |
Piroxicam |
Piroxicam |
11-46% |
| 1-2 HRS. |
Flurbiprofen |
Flurbiprofen |
15% |
| 1-2 HRS. |
Ibuprofen |
Ibuprofen |
15-39% |
| 4-5 HRS. |
Oxaprozin |
Oxaprozin |
13-25% |
| |
|
|
|
| Achieves peak
serum Concentration within 1 hour 1,2,3 |
| The most suitable NSAID for the treatment for Chronic,disabling
and life long Rheumatic Disorders due to it's: |
| |
|
| |
|
| |
|
- Better Efficacy
- Excellent Tolerability
- Less Side Effects
- Convenient dosage
|
 |
 |
References:
1. G. Spignoli, A fast acting Naproxen derivative for
pain relief. II. Clinical trials. European Bulletin of drug research.
Volume 4, No-1. January 1996.
2. The journal of international Medical Research -1988:
16:150-156.
3. American journal of Medicine. Vol.80 (Stippl.4-B)
April 28,1986.
4. G. spignoli, A fast acting Naproxen derivative for
pain relief 1 chemistry Pharmacology & Toxicology European Bulletin
of drug research. Volume 4 No. 1 January 1996. |
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